DSPE-PEG 2000 Azide

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DSPE-PEG 2000 Azide | CAS No. 1938081-40-3 | Lipid Nanoparticles
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Description: PEGylated DSPE with azide reactive group

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]

Purity: ≥90%

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Biological Activity

DSPE-PEG 2000 Azide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with an azide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used to make macrophage and EGFR antibody targeted LNPs using strain-promoted azide alkyne cycloaddition (SPAAC) click reaction.

Technical Data

Formula:
(C2H4O)nC44H84N4O10P.NH4
Solubility:
Soluble to 10 mg/ml in ethanol and to 10 mg/ml in chloroform
Purity:
≥90%
Storage:
Store at -20°C
CAS No:
1938081-40-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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