DSPE-PEG 2000 Azide

Name: DSPE-PEG 2000 Azide
Brand: Tocris Bioscience
SKU: 8837
Price: 140 USD
Availability: InStock

Tocris Bioscience | Catalog # 8837

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Product Documents

PEGylated DSPE with azide reactive group

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

PEGylated DSPE with azide reactive group

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Product Description

DSPE-PEG 2000 Azide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with an azide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used to make macrophage and EGFR antibody targeted LNPs using strain-promoted azide alkyne cycloaddition (SPAAC) click reaction.

Product Specifications for DSPE-PEG 2000 Azide

Formula

(C₂H₄O)_nC₄₄H₈₄N₄O₁₀P.NH₄

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]

CAS Number

1938081-40-3

PubChem ID

168311704

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 10mg/ml in chloroform and to 10mg/ml in Ethanol

Calculators

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Background References

References are publications that support the biological activity of the product.

Geisler EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. J.Control Release 2024 PMID: 38789090
Zhao Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proc.Natl.Acad.Sci.U.S.A. 2024 PMID: 38315853

Product Documents for DSPE-PEG 2000 Azide

Certificate of Analysis

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Product Specific Notices for DSPE-PEG 2000 Azide

For research use only

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