15 results for "Lipid Nanoparticle Components" in 产品

Lipid Nanoparticle Components

What are Lipid Nanoparticles?

Lipid nanoparticles (LNPs) are lipid based delivery systems commonly used for delivering bioactive nucleic acid payloads into living cells. LNPs are nanometer-sized particles (< 100 nm) comprised of a lipid monolayer shell surrounding an internal core packed with cargo molecules encapsulated in reverse micelles.

Figure 1: Structure and component of lipid nanoparticle carriers. Nucleic acid cargos are stabilized by the ionizable lipids and contained in reverse ...

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Liposome/lipoplex transfection enhancer

Chemical Name: (9Z)-1,1'-[(1R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] 9-octadecenoic acid ester
Purity: ≥95%
Liposome/lipoplex transfection enhancer
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Cationic cholesterol derivative

Chemical Name: (3β)-3-[N-[2-(Dimethylamino)ethyl]carbamate cholest-5-en-3-ol hydrochloride
Purity: ≥95%
Cationic cholesterol derivative
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Cationic agent for liposome and LNP formation

Alternate Names: 1,2-dioleoyl-3-trimethylammoniumpropane
Chemical Name: N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride
Purity: ≥90%
Cationic agent for liposome and LNP formation
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Neutral phospholipid; component of lipid nanoparticles (LNPs)

Alternate Names: 1,2-DSPC
Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity: ≥95%
Neutral phospholipid; component of lipid nanoparticles (LNPs)
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PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)

Chemical Name: 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
Purity: ≥90%
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
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Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity

Chemical Name: (3β)-Cholest-5-en-3-ol
Purity: ≥95%
Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity
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Component of lipid nanoparticles (LNPs); ionizable cationic lipid

Chemical Name: (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate
Purity: ≥95%
Component of lipid nanoparticles (LNPs); ionizable cationic lipid
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PEGylated DSPE with a maleimide reactive group

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)]
Purity: ≥90%
PEGylated DSPE with a maleimide reactive group
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PEGylated DSPE with azide reactive group

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]
Purity: ≥90%
PEGylated DSPE with azide reactive group
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Biotinylated DSPE PEG lipid

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000]
Purity: ≥90%
Biotinylated DSPE PEG lipid
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Ionizable cationic lipid

Chemical Name: 2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Purity: ≥95%
Ionizable cationic lipid
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Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB

Purity: ≥95%
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
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Nicotinic acetylcholine receptor targeting peptide for neuronal delivery

Purity: ≥95%
Nicotinic acetylcholine receptor targeting peptide for neuronal delivery
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Targeting peptide for the transferrin receptor (N-term Cys)

Purity: ≥95%
Targeting peptide for the transferrin receptor (N-term Cys)
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Cationic ionizable lipid

Chemical Name: 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate
Purity: ≥95%
Cationic ionizable lipid
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