dTAG-13-NEG

Name: dTAG-13-NEG
Brand: Tocris Bioscience
SKU: 6916
Price: 568 USD
Availability: InStock

Tocris Bioscience | Catalog # 6916

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Citations (2)

Product Documents

Negative control for dTAG-13 (Cat. No. 6605)

Product Description
Licensing Information
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Negative control for dTAG-13 (Cat. No. 6605)

View all TAG Degradation Platforms »

Product Description

dTAG-13-NEG is a negative control for dTAG-13 (Cat. No. 6605).

Licensing Information

Sold under license from Dana-Farber Cancer Institute

Product Specifications for dTAG-13-NEG

Molecular Weight

1063.19

Formula

C₅₈H₇₀N₄O₁₅

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2S)-2-piperidinecarboxylate (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester

CAS Number

2451573-90-1

InChI Key

ZKVNXENIWGNDDO-SKTJQTJUSA-N

SMILES

CC[C@@H](C1=CC(OC)=C(C(OC)=C1)OC)C(N2CCCC[C@H]2C(O[C@@H](C3=CC=CC=C3OCC(NCCCCCCOC4=CC=CC(C(N5C6CCC(N(C)C6=O)=O)=O)=C4C5=O)=O)CCC7=CC(OC)=C(C=C7)OC)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	106.32	100
	Ethanol	21.26	20

Preparing Stock Solutions for dTAG-13-NEG

The following data is based on the product molecular weight 1063.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	0.94 mL	4.70 mL	9.41 mL
5 mM	0.19 mL	0.94 mL	1.88 mL
10 mM	0.09 mL	0.47 mL	0.94 mL
50 mM	0.02 mL	0.09 mL	0.19 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

音量

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Nabet The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 2018 PMID: 29581585
Nabet Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nat.Commun. 2020 PMID: 32948771

Product Documents for dTAG-13-NEG

Download SDS

Product Specific Notices for dTAG-13-NEG

For research use only

Citations for dTAG-13-NEG

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