Q: Hi, I am looking for an antibody to human DUOX2 that will work on human formalin fixed paraffin embedded sections. I notice from your website that you have several recommended for WB and wondered if you have any experience of their use in other areas?

A: At this time we do not have an antibody for DUOX2 that works in IHC paraffin embedded sections. If you choose to try one in this application we have our Innovator's Reward program where we reward our customers for trying antibodies in previously untested applications and species.

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Rat DUOX2 ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP3-56027

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Product Specifications
Precision
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma, tissue homogenates and other biological fluids (100 uL)

Sensitivity

0.058 ng/mL (example only; lot dependent)

Assay Range

0.156 - 10 ng/mL (example only; lot dependent)

View all DUOX2 ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Rat

Description

Assay Length: 4.5 hours

精度

Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)

Kit Contents for Rat DUOX2 ELISA Kit (Colorimetric)

Pre-coated 96T strip plate, Plate sealer for 96 wells, Standard, Diluent Buffer, Detection Reagent A, Detection Reagent B, TMB Substrate, Stop Solution, Wash Buffer (30 x concentrate), Instruction manual

Preparation and Storage

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: DUOX2

Dual oxidase 2 (DUOX2), a reduced NAD phosphate:O2 oxidoreductase flavoprotein, plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with hydrogen peroxide, which is required for hormone synthesis at the apical plasma membrane. The discovery of DUOX-2 as a novel source of hydrogen peroxide in the digestive tract, particularly in the cecum and colon, makes it a new candidate mediator of physiopathological processes.

DUOX2 antibodies may be useful tools for thyroid hormone synthesis, hormonal regulation disorders, and certian types of cancer.

Alternate Names

dual oxidase 2, dual oxidase-like domains 2, EC 1.11.1.-, EC 1.6.3.1, flavoprotein NADPH oxidase, Large NOX 2, LNOX2P138(TOX), Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, nicotinamide adenine dinucleotide phosphate oxidase, NOXEF2, p138 thyroid oxidase, P138-TOX, THOX2TDH6, Thyroid oxidase 2

Gene Symbol

DUOX2

Additional DUOX2 Products

Product Documents for Rat DUOX2 ELISA Kit (Colorimetric)

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Certificate of Analysis

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Product Specific Notices for Rat DUOX2 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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