Discontinued Product
4320 has been discontinued.
View all Chemokine Receptor Antagonists products.
Product Description
CXCR4 antagonist (IC50 = 126 nM). Displays anti-HIV activity in assays using NL4-3 and IIIB strains (EC50 = 21 nM for both strains).
Product Specifications for FC 131
Molecular Weight
729.84
Formula
C36H47N11O6
Storage
Store at -20°C
CAS Number
606968-52-9
PubChem ID
5275848
InChI Key
MBXBICVKLVYNKD-QUAHOIDUSA-N
SMILES
NC(=N)NCCC[C@@H]1NC(=O)[C@@H](CC2=CC=C(O)C=C2)NC(=O)CNC(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@H](CCCNC(N)=N)NC1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Inokuchi Potent CXCR4 antagonists containing amidine type peptide bond isosteres. ACS Med.Chem.Lett.
- Tamamura Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131 J.Med.Chem. 2005 PMID: 15658852
Product Documents for FC 131
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FC 131
For research use only
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