Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

R&D Systems | Catalog # S12550H

This item is in process of being discontinued.
R&D Systems
Discontinued Product
S12550H has been discontinued. View all Fetal Bovine Serum (FBS) products.

Key Product Details

Features

Atlanta Biologicals Fetal Bovine Serum (FBS) – EU-approved, Heat-inactivated is a high-quality FBS that offers excellent value for basic cell culture as well as for specific research applications.

Key Benefits

  • Manufactured from EU-approved origin material
  • Heat-inactivated under a quality-controlled setting
  • Excellent cell growth characteristics, low endotoxin, and low hemoglobin values
  • Superior performance with a broad spectrum of cell types
  • More affordable alternative to other commercially available FBS
  • Available as 500 mL and 50 mL sizes

Applications

Cell Culture

Product Summary for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

Why Use Atlanta Biologicals Fetal Bovine Serum – EU – approved?
Fetal bovine serum (FBS), also known as Fetal Calf Serum (FCS), is the most commonly used media supplement for cells in culture. FBS is the ideal cell growth supplement and generally preferred over other types of cell culture sera. Its high levels of nutrients and optimal combination of growth factors makes FBS the most effective cell growth promoter for virtually any cell culture system. In addition, the significantly lower content of antibodies compared to adult and newborn sera minimizes the risk of antibody cross reaction with cells in culture. R&D Systems, a Bio-Techne brand, offers several grades of Atlanta Biologicals FBS, including one approved for use in Europe.
 
Why Use Heat-inactivated Fetal Bovine Serum?

The objective of heat inactivation is to destroy complement activity in the serum without affecting the growth-promoting characteristics of the product. Removal of complement activity from the serum is not required for most cell cultures, but may be necessary for cultures that are sensitive to the complement activity. Researchers should evaluate the applicability of heat inactivation in regards to their own application.

 
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Formulation, Preparation, and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at ≤ -20 °C in a manual defrost freezer. Do not use past the expiration date.

Background: Fetal Bovine Serum (FBS)

Fetal bovine serum (FBS), also known as fetal calf serum (FCS), is a commonly used cell culture media supplement. It supplies growth factors, hormones, vitamins, and other nutrients that can support the proliferation and viability of cells in culture. The range of these factors provided by FBS enables the culture of a wide variety of cell types that may have uncharacterized culture requirements. Heat inactivation of FBS destroys potentially detrimental complement proteins while retaining the growth-promoting properties of the serum. Specialty grades of FBS are optimized for the culture of particular cell types such as hybridomas, embryonic stem cells, tetracycline-controlled expression systems, and hormone dependent cells for insulin- and estrogen-related research. Manufacturers of FBS control product variability by managing the raw material supply chain, adhering to consistent processing protocols, and rigorous testing to ensure low endotoxin, hemoglobin, and virus load. USDA-approved testing of FBS is important to certify the virus and disease safety of the source before importing animal material into the United States. USDA APHIS certification enables the use of our US origin serum for the manufacture and export of products outside of the USA.

Product Documents for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

FOR LABORATORY RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

  • The safety and efficacy of this product in diagnostic or other clinical uses has not been established.
  • This reagent should not be used beyond the expiration date indicated on the label.
  • Results may vary due to variations among cells or cell lines used.

Citations for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated

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  • Q: What is the difference between Fetal Bovine Serum (FBS) and Fetal Calf Serum (FCS)?

    A: There is no difference. These are different names for the same product. Serum derived from blood of bovine fetuses is referred to as Fetal Bovine Serum or Fetal Calf Serum.

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