FGF-23 (fibroblast growth factor 23) is one of three FGF family members that appear to play a role in endocrine metabolism. It is described as being a phosphatonin, a molecule that reduces circulating plasma phosphate. FGF-23 does this, in part, by blocking Vitamin D activation. Active Vitamin D promotes intestinal phosphate absorption.
FGF-23 Antibody (283511) [DyLight 680]
Novus Biologicals | Catalog # FAB2629Y
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
DyLight 680 (Excitation = 692 nm, Emission = 712 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 283511
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse FGF-23
Tyr25-Val251 (Arg179Gln)
Accession # Q9EPC2
Tyr25-Val251 (Arg179Gln)
Accession # Q9EPC2
Specificity
Detects human and mouse FGF-23 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-3, -4, -5, -6, -7, -9, -10, -11, -12, -13, -16, -17, -18, -19, -20, -21, recombinant mouse (rm) FGF‑8b, rmFGF‑8c, or rmFGF-15.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for FGF-23 Antibody (283511) [DyLight 680]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGF-23
Long Name
Fibroblast Growth Factor 23
Alternate Names
FGF23
Gene Symbol
FGF23
Additional FGF-23 Products
Product Documents for FGF-23 Antibody (283511) [DyLight 680]
Product Specific Notices for FGF-23 Antibody (283511) [DyLight 680]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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