FGFR4 Antibody (137114) [mFluor Violet 500 SE]

Name: FGFR4 Antibody (137114) [mFluor Violet 500 SE]
Brand: Novus Biologicals
SKU: FAB685MFV500
Price: 579 USD
Availability: InStock

Novus Biologicals | Catalog # FAB685MFV500

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Product Documents

Clone 137114 was used by HLDA to establish CD designation

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

mFluor Violet 500 SE (Excitation = 410 nm, Emission = 501 nm)

Antibody Source

Monoclonal Mouse IgG_2A Clone # 137114

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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FGF R4
Met1-Asp369
Accession # P22455

Specificity

Detects human FGF R4 in direct ELISAs and Western blots. In Western blots, this antibody shows no cross-reactivity with any isoform of recombinant human (rh) FGF R1, rhFGF R2, rhFGF R3, recombinant mouse (rm) FGF R2, or rmFGF R3.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications for FGFR4 Antibody (137114) [mFluor Violet 500 SE]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Recommended applications are based on validated applications from the unconjugated base product MAB685. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FGFR4

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.

Long Name

Fibroblast Growth Factor Receptor 4

Alternate Names

CD334, FGF R4

Gene Symbol

FGFR4

Additional FGFR4 Products

Product Documents for FGFR4 Antibody (137114) [mFluor Violet 500 SE]

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for FGFR4 Antibody (137114) [mFluor Violet 500 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.