FITC-labelled Keap1-Nrf2 probe
Tocris Bioscience | Catalog # 7627
Key Product Details
Description
Wavelength
Product Description
FITC-labelled Keap1-Nrf2 probe is a fluorescent Keap1-Nrf2 peptide (Kd = 22.3 nM). It can be used to assess the binding affinities of Nrf2 peptide inhibitors in Fluorescence Polarization (FP) displacement assays and TR-FRET.Optical Data
| Emission Color | Green |
| λabs | 495 nm |
| λem | 525 nm |
| Closest Laser line | 488 nm |
| Application | Fluorescence polarization (FP) displacement assays, TR-FRET |
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Product Specifications for FITC-labelled Keap1-Nrf2 probe
Molecular Weight
Formula
Storage
Purity
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in PBS |
Calculators
Background References
References are publications that support the biological activity of the product.
- Inoyama Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction. J.Biomol.Screen 2012 PMID: 22156223
- Wang Development of an enzyme-linked immunosorbent assay for Keap1-Nrf2 interaction inhibitors identification. Redox Biol. 2020 PMID: 32422542
- Chen Kinetic analyses of Keap1-Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance. Chem.Biol.Drug Des. 2011 PMID: 21920027
Product Documents for FITC-labelled Keap1-Nrf2 probe
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FITC-labelled Keap1-Nrf2 probe
For research use only
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