GRB7 Antibody

Novus Biologicals | Catalog # NB100-1027

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Peptide with sequence ELDLSPPHLSSSPE-C corresponding to N-Terminus according to NP_005301.2.

Specificity

This antibody recognizes the longer isoform of this protein in A431 lysate.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Novus Biologicals Goat GRB7 Antibody (NB100-1027) is a polyclonal antibody validated for use in WB and ELISA. Anti-GRB7 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for GRB7 Antibody

Western Blot: GRB7 Antibody [NB100-1027]

Western Blot: GRB7 Antibody [NB100-1027]

Western Blot: GRB7 Antibody [NB100-1027] - Antibody at 1ug/ml. Staining of A431 lysate (35u g protein in RIPA buffer). Detected by chemiluminescence.

Applications for GRB7 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

1 - 3 ug/mL
Application Notes
Western blot: Approx 65 kDa band observed in lysates of cell line A431 (calculated MW of 59.7 kDa according to NP_005301.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GRB7

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

Long Name

Growth Factor Receptor-Bound Protein 7

Alternate Names

B47

Entrez Gene IDs

2886 (Human); 14786 (Mouse)

Gene Symbol

GRB7

Additional GRB7 Products

Product Documents for GRB7 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GRB7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Associated Pathways

Akt Signaling Pathway Akt Signaling Pathway Thumbnail