Human APBA3 Alexa Fluor™ Plus 647‑conjugated Antibody

R&D Systems | Catalog # AF5689AFP647

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Polyclonal Sheep IgG
View all APBA3 Primary Antibodies »

Product Specifications

Specificity

Detects human APBA3 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) X11‑ alpha and rhX11-beta is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human APBA3 Alexa Fluor™ Plus 647‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: APBA3

X11-gamma (Adaptor protein X11 gamma; also APBA3, Mint3 and X11L2) is a member of the X11 family of adaptor proteins. Unlike X11 alpha and -beta which are generally neuronal proteins, X11-gamma is widely expressed in all tissues. X11-gamma has many functions, including MT-MMP and Furin intracellular trafficking and APP binding. Human X11-gamma is 575 amino acids (aa) in length. It contains a poly-Ser segment (aa 165‑171), a PID region (aa 217‑381) that binds beta -amyloid precursor, and two PDZ domains (aa 393‑478 and 485‑560) that bind Arf GTPases. There is one potential splice variant that shows a 34 aa insertion after Ile505. Over aa 1‑138, human X11‑ gamma shares 62% aa identity with mouse X11‑ gamma.

Long Name

Amyloid Beta [A4] Precursor Protein-binding, Family A, Member 3

Alternate Names

MINT3, X11L2

Entrez Gene IDs

9546 (Human); 57267 (Mouse); 83611 (Rat)

Gene Symbol

APBA3

UniProt

O96018 (Human)

Additional APBA3 Products

Product Documents for Human APBA3 Alexa Fluor™ Plus 647‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human APBA3 Alexa Fluor™ Plus 647‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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