The name of Aminopetidase PILS (Puromycin-insensitive Leucyl-specific) describes the two basic properties of this zinc metalloproteinase in vitro. Also known as ALAP (Adipocyte-derived Leucine Aminopeptidase), Aminopeptidase regulator of TNFR1 shedding 1 (ARTS1), and ER Aminopeptidase ERAP1 or ERAAP, it is encoded by the ARTS1 gene. Aminopeptidase PILS is thought to regulate antigen presentation, promote TNFR1 and IL-6 R ectodomain shedding, and may be associated with hypertension.
Human ARTS1 (AAF07395) VersaClone cDNA
R&D Systems | Catalog # RDC2754
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Aminopeptidase PILS/ARTS1
Long Name
Aminopeptidase Puromycin-insensitive Leucyl-specific
Alternate Names
A-LAP, ARTS1, ERAAP1, ERAP1, PILS-AP
Gene Symbol
ERAP1
UniProt
Additional Aminopeptidase PILS/ARTS1 Products
Product Documents for Human ARTS1 (AAF07395) VersaClone cDNA
Product Specific Notices for Human ARTS1 (AAF07395) VersaClone cDNA
For research use only
Related Research Areas
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