Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA

R&D Systems | Catalog # RDC0951

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Key Product Details

Species

Human

Accession Number

NP_001703

Background: CEACAM-1/CD66a

CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic region. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 1

Alternate Names

BGP1, Biliary Glycoprotein 1, CD66a, Cea-1, CEACAM1, Hv-1, Hv-2, MHVR

Entrez Gene IDs

634 (Human); 26365 (Mouse); 102139857 (Cynomolgus Monkey)

Gene Symbol

CEACAM1

UniProt

NP_001703

Additional CEACAM-1/CD66a Products

Product Documents for Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA

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Product Specific Notices for Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA

For research use only

Citations for Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA

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  • Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA
    Name: Anonymous
    Verified Customer | Posted 10/28/2018
    over-expression in 293T cell and western blot, seems like good
    Human CEACAM-1/CD66a (NP_001703) VersaClone cDNA RDC0951

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