Human Chondromodulin-1 Antibody (394002)

R&D Systems | Catalog # MAB41681

R&D Systems

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 394002
View all Chondromodulin-1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Chondromodulin‑1 mature chain
Glu215-Val333
Accession # NP_001011705.1

Specificity

Detects human Chondromodulin‑1 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human Chondromodulin-1 Antibody (394002)

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human Chondromodulin‑1

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Chondromodulin-1

Chondromodulin-1 (ChM-1), also known as Lect1, is a type II transmembrane protein that is cleaved intracellularly resulting in the secretion of a 25 kDa molecule. ChM-1 is expressed in avascular cartilage, cardiac valves, and the eye. The antiangiogenic properties of ChM-1 can block tumor progression and the pathological vascularization of cardiac valves. Human ChM-1 shares 89%‑92% aa sequence identity with bovine, mouse, rabbit, and rat ChM-1.

Alternate Names

BRICD3, ChM-1, Chondromodulin1, LECT1

Entrez Gene IDs

11061 (Human); 16840 (Mouse); 81512 (Rat)

Gene Symbol

CNMD

UniProt

NP_001011705.1

Additional Chondromodulin-1 Products

Product Documents for Human Chondromodulin-1 Antibody (394002)

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Chondromodulin-1 Antibody (394002)

For research use only

Citations for Human Chondromodulin-1 Antibody (394002)

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