Human DLL3 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB4315V Datasheet / COA / SDS

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FAB4315V-100UG

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Human DLL3 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human DLL3 in direct ELISAs and Western blots. Does not cross‑react with recombinant human (rh) DLL1 or rhDLL4.

Source

Monoclonal Mouse IgG2b Clone # 378703

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human DLL3
Ala27-Pro488
Accession # Q9NYJ7

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DLL3

Delta-like 3 (DLL3) is a transmembrane Delta-like protein that contains one DSL domain and six EGF-like repeats. DLL3 is critical for somite segmentation and neurogenesis during early embryonic development. It does not bind Notch receptors but functions as an antagonist of Notch signaling. Defects in DLL3 cause axial skeletal abnormalities in spondylocostal dysostosis. Within the extracellular domain, human DLL3 shares 84% amino acid sequence identity with mouse and rat DLL3.

Long Name

Delta-like 3

Entrez Gene IDs

10683 (Human); 13389 (Mouse); 114125 (Rat)

Alternate Names

delta (Drosophila)-like 3; Delta3; delta-like 3 (Drosophila); delta-like protein 3; DLL3; Drosophila Delta homolog 3; Pudgy; SCDO1; SCDO1delta3