Human DPP10 Alexa Fluor® 405-conjugated Antibody

Catalog #: AF4100V Datasheet / COA / SDS

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AF4100V-100UG

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Human DPP10 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human DPP10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human (rh) DPP6 and rhDPP4 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human DPP10
Leu56-Glu796 (Pro340Ala)
Accession # NP_065919

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DPP10

DPP10 (dipeptidyl peptidase 10; also DPPY, DPRP3 and DPL2) is a 91‑97 kDa member of the peptidase S9B family. It is a type II transmembrane glycoprotein principally expressed in neurons and T cells. Although it is a peptidase member, it has no catalytic activity. Instead, it assists in the membrane trafficking and functioning of Kv4 K⁺ channels. Human DPP10 is 796 amino acids (aa) in length. It contains a 34 aa cytoplasmic N-terminus and a 741 aa extracellular domain (ECD) (aa 56‑796). Three potential isoforms exist, all involving aa substitutions limited to the first 20 amino acids. The ECD of human DPP10 shares 89% aa sequence identity with mouse DPP10 ECD.

Long Name

Dipeptidyl-peptidase 10

Entrez Gene IDs

57628 (Human); 269109 (Mouse); 363972 (Rat)

Alternate Names

dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; dipeptidyl peptidase like protein 2; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (non-functional); dipeptidyl-peptidase 10; DPL2; DPP X; DPP10; DPPY; DPRP3; DPRP-3; DPRP3dipeptidylpeptidase 10; inactive dipeptidyl peptidase 10; KIAA1492