Human FGFR1 (IIIb) Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB765S Datasheet / COA / SDS

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FAB765S-100UG

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Human FGFR1 (IIIb) Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects IIIb isoforms of human FGF R1. In direct ELISAs and Western blots, this antibody detected IIIb but not IIIc isoforms of human FGF R1, human FGF R2, and mouse FGF R2. In direct ELISA, approximately 20% cross-reactivity was observed with r

Source

Monoclonal Mouse IgG1 Clone # 133111

Purification

Protein A or G purified

Immunogen

A mixture of purified isoforms of recombinant human FGF R1 extracellular domains

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Neutralization

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FGFR1

FGF R1 occurs as multiple isoforms. The extracellular domain consists of three ( alpha isoforms) or two ( beta isoforms) immunoglobulin-like domains. In addition, the membrane-proximal Ig-like domain can be encoded by alternative exons yielding (IIIb) or (IIIc) isoforms.

Long Name

Fibroblast Growth Factor Receptor 1

Entrez Gene IDs

2260 (Human); 14182 (Mouse)

Alternate Names

basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; CD331 antigen; CD331; CEK; EC 2.7.10; EC 2.7.10.1; FGF R1; FGFBR; FGFR1; FGFR-1; fibroblast growth factor receptor 1; FLGH3; FLJ99988; Flt-2; FLT2H4; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; H2; H5; HBGFR; heparin-binding growth factor receptor; hydroxyaryl-protein kinase; KAL 2; KAL2; N-SAM; OGD; Proto-oncogene c-Fgr; soluble FGFR1 variant 1; soluble FGFR1 variant 2