Human HHEX Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB8377X Datasheet / COA / SDS

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FAB8377X-100UG

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Human HHEX Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human HHEX in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 906705

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human HHEX
Thr111-Gly270
Accession # Q03014

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: HHEX

Hematopoietically-expressed homeobox protein (HHEX), also known as HEX, PRH and PRHX, is a 35-40 kDa member of the Homeobox family of transcription factors. Family members are distinguished by an evolutionarily conserved DNA-binding homeodomain of 60 amino acids (aa), which for HHEX spans aa 137-196. Human HHEX was initially isolated from hematopoietic tissue, and is present in several hematopoietic progenitors, where its expression is down-regulated during terminal cell differentiation. HHEX is also expressed in the anterior visceral endoderm during early mouse development, and in some adult tissues of endodermal origin, including liver, lung and thyroid. HHEX knockout in mice is embryonic lethal, with impaired forebrain, liver and thyroid development. Human HHEX is 270 aa in length, and over aa 111-270, shares 93% and 95% identity with mouse and rat HHEX, respectively.

Long Name

Hematopoietically Expressed Homeobox

Entrez Gene IDs

3087 (Human); 15242 (Mouse); 79237 (Rat)

Alternate Names

hematopoietically expressed homeobox; Hex; HEXHMPH; HHEX; HMPH; Homeobox protein HEX; Homeobox protein PRH; HOX11L-PEN; PRH; PRHhematopoietically-expressed homeobox protein HHEX; PRHX; PRHXhomeobox, hematopoietically expressed; proline-rich homeodomain-containing transcription factor