Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA

Name: Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3435
Price: 675 USD
Availability: InStock

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_690008.2

Background: HIF-3 alpha/HIF3A

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, by transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Long Name

Hypoxia Inducible Factor 3 Subunit Alpha

Alternate Names

BHLHe17, HIF3A, IPAS, MOP7, PASD7

Entrez Gene IDs

64344 (Human)

Gene Symbol

HIF3A

UniProt

NP_690008.2

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Product Specific Notices for Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA

For research use only

Related Research Areas

Basic Helix-Loop-Helix (bHLH) Transcription Factors

Epigenetics

Hypoxia Inducible Factors (HIFs)

Notch Pathway

Transcription Factors in the Akt Pathway

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