Transcription Factors in the Akt Pathway
Signal transduction often culminates in the activation of transcription factors, a specialized subset of proteins capable of interacting with DNA to either up- or downregulate the transcription of genes. Transcription factor binding is often specific for certain DNA sequences. They are highly regulated with respect to cytoplasmic vs. nuclear localization, stabilization, and post-translational modification. The transcription factors listed below have all been associated with Akt pathway activation, which promotes cell growth, survival, proliferation, autophagy, and metabolism. The activity of these transcription factors is either up- or downregulated by Akt signaling.
bHLH Transcription Factors in the Akt Pathway
bZIP Transcription Factors in the Akt Pathway
ETS Family Transcription Factors in the Akt Pathway
Forkhead Domain Transcription Factors in the Akt Pathway
GATA Transcription Factors
HMG Transcription Factors in the Akt Pathway
Hox Transcription Factors in the Akt Pathway
Ig-like Domain Transcription Factors in the Akt Pathway
IRF Family Transcription Factors in the Akt Pathway
Kruppel-like Transcription Factors in the Akt Pathway
Other Transcription Factors in the Akt Pathway
Paired Box Transcription Factors in the Akt Pathway
Smad Transcription Factors in the Akt Pathway