Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 326903
View all INSRR Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human INSRR
Leu24-Leu923
Accession # P14616

Specificity

Detects human INSRR in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human Insulin receptor is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human INSRR Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human INSRR

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: INSRR

INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family.It is expressed in neuroblastoma and many adult tissues, including kidney, heart, pancreas, liver and skeletal muscle. INSRR is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. The extracellular domain of human INSRR shares approximately 90% amino acid sequence identity with the mouse protein.

Long Name

Insulin Receptor-related Receptor

Alternate Names

IRR

Entrez Gene IDs

3645 (Human); 23920 (Mouse)

Gene Symbol

INSRR

UniProt

P14616

Additional INSRR Products

Product Documents for Human INSRR Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human INSRR Antibody

For research use only

Citations for Human INSRR Antibody

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