MBP-1 (eosinophil major basic protein), also known as PRG2 (proteoglycan 2) can be found in two forms: a 33 kDa glycosylated secreted proprotein form that circulates especially in pregnancy, or a 14 kDa mature protein. Covalent association with proMBP-1 inhibits the activity of proteins such as PAPP-A (pregnancy-associated plasma protein-A), heparanase and angiotensinogen. In contrast, mature MBP-1 is present in eosinophil and basophil granules and mainly plays an antimicrobial role.
Human MBP-1 (NP_002719) VersaClone cDNA
R&D Systems | Catalog # RDC2412
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Background: MBP-1
Long Name
Major basic protein
Alternate Names
BMPG, EMBP, PRG2
Gene Symbol
PRG2
UniProt
Additional MBP-1 Products
Product Documents for Human MBP-1 (NP_002719) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human MBP-1 (NP_002719) VersaClone cDNA
For research use only
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