Human/Mouse MafK Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB3809V Datasheet / COA / SDS

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FAB3809V-100UG

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Human/Mouse MafK Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse MafK in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) MafB or rhMafF is observed. In Western blots, prolonged film exposures may slightly detect rhMafG.

Source

Monoclonal Mouse IgG2b Clone # 381923

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human MafK
Thr2-Ser156
Accession # O60675

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MafK

Maf family members form a unique subclass of basic-leucine zipper (bZIP) transcription factors. Maf proteins are subdivided into two groupings: large, including c‑Maf, Nrl, MafA, and MafB; and small, including MafF, MafG, and MafK, also known as p18. Large Mafs contain an N-terminal acidic domain important for transcriptional activation that is lacking in small Maf family members. Heterodimers of MafK and p45 NF-E2, another bZIP factor, promote globin gene expression and erythroid differentiation in erythroleukemia cells.

Long Name

v-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog K

Entrez Gene IDs

7975 (Human); 17135 (Mouse)

Alternate Names

FLJ32205; MafK; MGC71717; NFE2U; transcription factor MafK; ubiquitous (p18); v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein K; v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)