OMgp is a GPI-anchored protein derived from myelin. It is expressed on oligodendrocytes and neurons and binds to a receptor complex consisting of the Nogo receptor and the p75 neurotrophin receptor, NGF R. OMgp is active in the inhibition of axonal outgrowth as well as regeneration following injury.
OMgp Antibody (240527)
R&D Systems | Catalog # MAB1674
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Mouse
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG1 Clone # 240527
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OMgp
Ile25-Ser420
Accession # Q63912
Ile25-Ser420
Accession # Q63912
Specificity
Detects human and mouse OMgp in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human OMgp is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG1
Applications for OMgp Antibody (240527)
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)
Sample: Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: OMgp
Long Name
Oligodendrocyte-Myelin glycoprotein
Alternate Names
OMG
Gene Symbol
OMG
UniProt
Additional OMgp Products
Product Documents for OMgp Antibody (240527)
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for OMgp Antibody (240527)
For research use only
Related Research Areas
Citations for OMgp Antibody (240527)
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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