Human/Mouse/Rat FKBP13 Alexa Fluor™ Plus 555‑conjugated Antibody

R&D Systems | Catalog # AF4356AFP555

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Alexa Fluor Plus 555 (Excitation = 558 nm, Emission = 572 nm)

Antibody Source

Polyclonal Sheep IgG
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Product Specifications

Specificity

Detects endogenous human, mouse, and rat FKBP13 in Western blots. In Western blots, this antibody does not cross‑react with recombinant human FKBP12, FKBP25, FKBP38, FKBP51 or FKBP52.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human/Mouse/Rat FKBP13 Alexa Fluor™ Plus 555‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FKBP13

FK506 binding protein, 13 kilodalton molecular weight (FKBP13), also called FKBP2, is a peptidyl-prolyl isomerase that catalyzes the transition between cis- and trans‑proline residues critical for proper folding of proteins. The immunosuppressants FK506 and rapamycin are potent inhibitors of FKBP13. This isomerase is localized in the endoplasmic reticulum and is also associated with cytoskeletal elements such as erythrocyte band 4.1. FKBP13 levels are increased by treatments that affect golgi protein processing such as tunicamycin and heat shock, suggesting that FKBP13 is important in the unfolded protein response observed with endoplasmic reticulum stress.

Long Name

13 kDa FK506 Binding Protein

Alternate Names

FKBP2

Entrez Gene IDs

2286 (Human); 14227 (Mouse); 25639 (Rat)

Gene Symbol

FKBP2

UniProt

Additional FKBP13 Products

Product Documents for Human/Mouse/Rat FKBP13 Alexa Fluor™ Plus 555‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse/Rat FKBP13 Alexa Fluor™ Plus 555‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

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