Human/Mouse/Rat Lipin 2 Alexa Fluor® 594-conjugated Antibody

Catalog #: AF3756T Datasheet / COA / SDS

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AF3756T-100UG

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Human/Mouse/Rat Lipin 2 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects Lipin 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Lipin 1 and rhLipin 3 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Lipin 2
Ser439-Lys563
Accession # Q92539

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Lipin 2

Human Lipin 2 is a 100 kDa (896 aa) nuclear protein that belongs to the large, evolutionarily conserved Lipin family. All Lipin family members have a conserved N‑lipin domain at the N‑termini, a nuclear localization signal, and a conserved C-lipin domain near the C-termini. The functions of the N- and C-lipin domain are not known. Lipin 2 is widely expressed. Mutations in human Lipin 2 have been associated with autosomal dominant high grade myopia and Majeed syndrome. Over the region used as immunogen, human and mouse Lipin 2 are 100% identical. Lipin 2 also shares approximately 48% - 50% amino acid sequence identity with Lipin 1 and Lipin 3.

Long Name

Phosphatidate Phosphatase LPIN2

Entrez Gene IDs

9663 (Human); 64898 (Mouse); 316737 (Rat)

Alternate Names

EC 3.1.3.4; KIAA0249lipin-2; Lipin 2; Lipin-2; LPIN2; phosphatidate phosphatase LPIN2