Human/Mouse/Rat PIM2 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB4355V Datasheet / COA / SDS

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FAB4355V-100UG

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Human/Mouse/Rat PIM2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human, mouse, and rat PIM2 in Western blots. In Western blots, no cross-reactivity with recombinant human PIM1 or PIM3 is observed.

Source

Monoclonal Mouse IgG2b Clone # 447023

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PIM2
Met1-Pro311
Accession # Q9P1W9

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PIM2

The three members of the Pim family of proto-oncogenes encode the serine/threonine kinases PIM1, PIM2, and PIM3. Multiple isoforms of PIM2 are expressed in many tissues, with high levels in spleen, thymus, testis, small intestine, and colon. PIM2 is implicated as a mediator of IL-3 survival signaling in hematopoietic cells, and dysregulated PIM2 expression is observed in prostate cancer, lymphoma, leukemia, and multiple myeloma.

Long Name

Proviral Integration Site 2

Entrez Gene IDs

11040 (Human); 18715 (Mouse); 317366 (Rat)

Alternate Names

EC 2.7.11.1; pim-2 oncogene; PIM2; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2