Human Neurogenin-1 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB3524V Datasheet / COA / SDS

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FAB3524V-100UG

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Human Neurogenin-1 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Neurogenin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Neurogenin-3 is observed.

Source

Monoclonal Mouse IgG1 Clone # 309707

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Neurogenin‑1
Ala145-His237
Accession # NP_006152

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Neurogenin-1

Neurogenin-1 is a 26 kDa developmentally expressed nuclear protein of the basic helix-loop-helix (bHLH) family, class B subfamily. bHLH proteins are transcription factors that form dimers to bind DNA. NGN1 is expressed only in embryonic neural tissue and supports neuronal differentiation but inhibits glial cell differentiation. Human Neurogenin-1 shows 93% amino acid identity with both mouse and rat Neurogenin-1 over the sequence used as an immunogen.

Entrez Gene IDs

4762 (Human); 18014 (Mouse)

Alternate Names

AKA; BHLHA6; bHLHa6NGN-1; Class A basic helix-loop-helix protein 6; Math4C; NEUROD3; NEUROD3neurogenic differentiation 3; NEUROG1; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; neurogenin 1; Neurogenin1; Neurogenin-1; NGN; ngn1