Human NOMO Alexa Fluor® 700-conjugated Antibody

Catalog #: AF3755N Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3755N-100UG

Save 15% on Select RUO Reagents. See Details.

All NOMO Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human NOMO Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human NOMO in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human NOMO
Ser32- Asp1155
Accession # Q15155

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: NOMO

NOMO, also known as pM5, is a 130 kDa type I membrane protein with no recognizable functional motif. It is a binding partner of Nicalin, a nicastin-related protein. The Nicalin/NOMO complex is localized in the ER and functions as an antagonist for Nodal and Activin signaling. Three copies of the NOMO gene, encoding NOMO isoforms 1, 2 and 3 have been described. The extracellular domains (ECD) of the isoforms share 99% amino acid sequence homology. The ECD of human and mouse NOMO also share 94% amino acid sequence homology.

Long Name

NODAL Modulator

Entrez Gene IDs

283820 (Human)

Alternate Names

NOMO; NOMO2; PM5