Human Opticin Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB3148X Datasheet / COA / SDS

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FAB3148X-100UG

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All Opticin Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Opticin Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Opticin in direct ELISAs and Western blots. In direct ELIAs and Western blots, no cross-reactivity with recombinant mouse Opticin is observed.

Source

Monoclonal Rat IgG2a Clone # 361328

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Opticin
Ala20-Thr332
Accession # Q9UBM4

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Opticin

Opticin (Oculoglycan) is a member of the small leucine-rich proteoglycan (SLRP) family with homology to class III extracellular matrix family members Epiphycan and Mimecan. It forms a 90 kDa noncovalent dimer that is a component of vitreous collagen fibrils in the eye and is also expressed in the retina, iris, ligaments and skin. Mature human Opticin shares 73% and 65% aa identity with mouse and rat, respectively. Mutations of Opticin have been associated with age-related macular degeneration.

Entrez Gene IDs

26254 (Human); 269120 (Mouse)

Alternate Names

oculoglycan; Oculogylcan; OPT; OPTC; Opticin