Human PDGF-B Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB220T-100UG

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Human PDGF-B Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human PDGF-B subunit in direct ELISAs and Western blots. In direct ELISAs, shows approximately 40% cross‑reactivity with recombinant human (rh) PDGF‑AB and no cross-reactivity with rhCTGF, rhLDGF, rhPDGF‑AA, recombinant rat (rr) PDGF‑AA, rrPD
Source
Monoclonal Mouse IgG1 Clone # 108132
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human PDGF‑BB
Ser82-Thr190
Accession # P01127
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PDGF-B

Four PDGF family members, A, B, C and D, have been identified. PDGF-B can exist as a disulfide-linked homodimer (PDGF-BB) or heterodimer (PDGF-AB). PDGF-B binds and activates PDGF R alpha and PDGF R beta.

Long Name
Platelet-derived Growth Factor B
Entrez Gene IDs
5155 (Human); 24628 (Rat); 100070283 (Equine)
Alternate Names
B chain; Becaplermin; C-Sis; FLJ12858; IBGC5; PDGF subunit B; PDGF2; PDGF-2; PDGFB; PDGF-B; platelet-derived growth factor 2; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis)oncogene homolog); Platelet-derived growth factor beta polypeptide; platelet-derived growth factor subunit B; platelet-derived growth factor, B chain; Platelet-derived growth factor, beta polypeptide (oncogene SIS); Proto-oncogene c-Sis; SIS; SSV

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