Human RSK4 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB3916T Datasheet / COA / SDS

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FAB3916T-100UG

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Human RSK4 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human RSK4 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) RSK1, rhRSK2, or rhRSK3 is observed.

Source

Monoclonal Rat IgG2a Clone # 374521

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human RSK4
Met1-Leu745
Accession # Q9UK32

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: RSK4

The 90 kDa ribosomal protein S6 kinases (RSK1-4) are a family of broadly expressed Ser/Thr kinases frequently activated in response to mitogenic stimuli, including growth factors and tumor-promoting phorbol esters. RSK4, also known as RPS6KA6, is commonly deleted in patients with complex X-linked mental retardation. Unlike other RSKs, RSK4 is constitutively active in serum-starved cells, and may participate in non-growth factor signaling.

Long Name

Ribosomal Protein S6 Kinase IV

Entrez Gene IDs

27330 (Human); 67071 (Mouse); 317203 (Rat)

Alternate Names

EC 2.7.11; EC 2.7.11.1; p90-RSK 6; p90RSK6; pp90RSK4; PP90RSK4,90 kDa ribosomal protein S6 kinase 6; ribosomal protein S6 kinase alpha-6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; Ribosomal S6 kinase 4; RPS6KA6; RSK4; RSK-4; RSK4ribosomal protein S6 kinase, 90kD, polypeptide 6; S6K-alpha 6; S6K-alpha-6