Human SOX5 Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # AF5286AFP488

R&D Systems
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG
View all SOX5 Primary Antibodies »

Product Specifications

Specificity

Detects endogenous human SOX5 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human SOX5 Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SOX5

SOX5 (SRY-related HMG box) is a 75‑80 kDa Group D member of the SOX family of DNA-binding proteins. It is expressed in fetal chondrocytes and skeletal muscle, with a short form appearing in spermatids. SOX5 form homodimers and heterodimerizes with SOX6. Human SOX5 is 763 amino acids (aa) in length and contains two coiled-coil regions (aa 193‑274 and 448‑515), plus one Q/glutamine (aa 234‑272) and one HMG box (aa 556‑624). HMG domains participate in DNA-binding and protein‑protein interaction. There are two alternate start sites at Met14 and Met417 (which creates a short/testis form), plus one variant with a three aa substitution for aa 389‑763, another variant with a two aa substitution for aa 1‑388, and a third variant with a one aa substitution for aa 534‑763. Over aa 417‑763, human SOX5 is 97% aa identical to mouse SOX5.

Long Name

SRY-related HMG-box 5

Alternate Names

L-SOX5

Entrez Gene IDs

6660 (Human); 20678 (Mouse); 312831 (Rat)

Gene Symbol

SOX5

UniProt

P35711

Additional SOX5 Products

Product Documents for Human SOX5 Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human SOX5 Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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