Human STAT1 Alexa Fluor® 532-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: STAT1

STAT1 is a member of the STAT family of cytoplasmic transcription factors that mediate cytokine, growth factor and hormone receptor signal transduction. STAT1 is associated with type I and II interferon signaling. Phosphorylation of STAT1a at Y701 leads to dimerization and translocation to the nucleus to activate gene transcription. Human STAT1 shows 93% and 94% aa identity with mouse and rat STAT1, respectively, over the region used as an immunogen. This region is identical between isoforms STAT1a (91 kDa) and STAT1b (84 kDa).

Product Datasheets

Related Research Areas

• Apoptosis Transcription Factors and Regulators
• B Cell Markers
• Chemokine Receptor Intracellular Signaling
• Common gamma Chain Receptor Family
• IL-10 and Interferon Family Regulators
• IL-10 Family
• IL-12 Family
• Immunoglobulin-Like Domain Transcription Factors
• Interferons
• Intracellular Signaling Molecules in Angiogenesis
• Jak and STAT Proteins
• Macrophage Activation Markers
• Mesenchymal Stem Cell Transcription Factors
• Myeloid-derived Suppressor Cells (MDSC)
• PDGF Family
• STAT
• Th1 Cells
• Transcription Factors in the Akt Pathway
• Transcriptional Regulators in Allergy and Asthma