Human TBX2 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB5040G Datasheet / COA / SDS

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FAB5040G-100UG

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Human TBX2 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects endogenous human TBX2 in Western blots at approximately 75 kDa.

Source

Monoclonal Rat IgG2b Clone # 393725

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human TBX2
Thr593-Arg702
Accession # Q13207

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TBX2

TBX2 (T-box transcription factor 2) is a member of a family of transcription factors that share the T-box DNA binding domain. TBX2, as well as other TBX proteins, is involved in remodeling of the heart myocardium through a complex spatial and temporal regulation. TBX2 is associated with tumorigenesis and anti-senescence properties by affecting several cyclin-dependent kinase inhibitors. The full-length protein contains 702 amino acids with a DNA binding domain from aa 99 to aa 277.

Long Name

T-box Transcription Factor 2

Entrez Gene IDs

6909 (Human); 21385 (Mouse); 303398 (Rat)

Alternate Names

FLJ10169; T-box 2; T-box protein 2; T-box transcription factor TBX2; TBX2