Human VEGFR1/Flt-1 Quantikine ELISA Kit

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DVR100C
PDVR100C
SVR100C
Control Products Available
Human VEGF R1/Flt-1 Standard Curve
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Product Details
Citations (66)
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Human VEGFR1/Flt-1 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Cell Lysates (10 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Saliva (100 uL)
Sensitivity
8.46 pg/mL
Assay Range
31.3 - 2,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva)
Specificity
Natural and recombinant human VEGF R1.
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine® Human VEGF R1/Flt-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF R1 in cell culture supernates, cell lysates, serum, plasma, and saliva. It contains NS0-expressed recombinant human VEGF R1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human VEGF R1 showed linear curves that were parallel to the standard curves obtained using the Quantikine® kit standards. These results indicate that this kit can be used to determine relative mass values for natural human VEGF R1.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components

Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 207 610 1207 207 616 1205
Standard Deviation 5.16 14.9 35.6 13.9 38.9 74
CV% 2.5 2.4 2.9 6.7 6.3 6.1

Recovery

The recovery of human VEGF R1 spiked to levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=4) 99 87-110
Cell Lysis Buffer (n=4) 94 86-108
EDTA Plasma (n=4) 92 84-98
Heparin Plasma (n=4) 89 81-96
Saliva (n=4) 109 96-124
Serum (n=4) 104 93-114

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of human VEGF R1 were serially diluted with calibrator diluent to produce samples with values within the dynamic range of the assay.
Human VEGF R1/Flt-1 ELISA Linearity
Human VEGF R1/Flt-1 ELISA Linearity

Data Examples

Human VEGF R1/Flt-1 Standard Curve

Human VEGF R1 Quantikine ELISA Kit Linearity Competitor Comparison

Human VEGF R1 Quantikine ELISA Kit Sensitivity Competitor Comparison

Human VEGF R1 Quantikine ELISA Kit Interference Competitor Comparison

Human VEGF R1/Flt-1 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: VEGFR1/Flt-1

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Long Name:
Vascular Endothelial Growth Factor Receptor 1
Entrez Gene IDs:
2321 (Human); 14254 (Mouse)
Alternate Names:
EC 2.7.10; EC 2.7.10.1; FLT; FLT1; Flt-1; Fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor); FRT; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Human VEGFR1/Flt-1 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

66 Citations: Showing 1 - 10
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  1. Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia
    Authors: RA Rahman, P Murthi, H Singh, S Gurungsing, B Leaw, JC Mockler, R Lim, EM Wallace
    Int J Mol Sci, 2020;21(7):.
    Species: Human
    Sample Types: Placenta
  2. Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy
    Authors: DL Wilson, ME Howard, AM Fung, FJ O'Donoghue, M Barnes, M Lappas, SP Walker
    PLoS ONE, 2020;15(4):e0232287.
    Species: Human
    Sample Types: Plasma
  3. ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia
    Authors: P Villie, G Lefevre, R Arrestier, A Rousseau, N Berkane, A Hertig
    Am. J. Obstet. Gynecol., 2019;220(3):284-285.
    Species: Human
    Sample Types: Plasma
  4. A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells
    Authors: C Abou Fayca, S Gazzeri, B Eymin
    Sci Rep, 2019;9(1):336.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Anti-angiogenic efficacy in invasive breast carcinoma patients depends on clinicopathological determinants
    Authors: E Zarychta, P Rhone, K Bielawski, M Michalska, D Ro??, B Ruszkowska
    Adv Med Sci, 2019;64(2):216-223.
    Species: Human
    Sample Types: Plasma
  6. Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection
    Authors: HW Unger, AP Hansa, C Buffet, W Hasang, A Teo, L Randall, M Ome-Kaius, S Karl, AA Anuan, JG Beeson, I Mueller, SJ Stock, SJ Rogerson
    Sci Rep, 2019;9(1):2260.
    Species: Human
    Sample Types: Plasma
  7. Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia
    Authors: M Varas-Godo, S Acuña-Gall, S Venegas-Du, C Hill, A Caceres-Ve, O Realini, LJ Monteiro, G Zavala, M Khoury, R Romero, G Rice, SE Illanes
    Stem Cells Int, 2019;2019(0):1916542.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Systemic Inflammation Precedes Microalbuminuria in Diabetes
    Authors: FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk,
    Kidney Int Rep, 2019;4(10):1373-1386.
    Species: Human
    Sample Types: Serum
  9. Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat
    Authors: MS Dias, VG Araujo, T Vasconcelo, Q Li, WW Hauswirth, R Linden, H Petrs-Silv
    Gene Ther., 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  10. LIFR increases the release of sEng via the up-regulation of MMP14 expression in PE
    Authors: H Li, J Yao, X Chang, J Wu, T Duan, K Wang
    Reproduction, 2018;0(0):.
    Species: Human
    Sample Types: Plasma
  11. Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis
    Authors: H Tanaka, K Kumasawa, A Kakigano, K Mimura, M Endo, T Tomimatsu, T Kimura
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts
    Authors: GS Stødle, GB Silva, LH Tangerås, LM Gierman, I Nervik, UE Dahlberg, C Sun, MH Aune, LCV Thomsen, L Bjørge, AC Iversen
    Clin. Exp. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Serum
  13. Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization
    Authors: SHS Lee, HJ Kim, OK Shin, JS Choi, J Kim, YH Cho, J Ha, TK Park, JY Lee, K Park, H Lee
    Invest. Ophthalmol. Vis. Sci., 2018;59(13):5398-5407.
    Species: Human
    Sample Types: Cell Lysates
  14. Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice
    Authors: JA Sandgren, G Deng, DW Linggonego, SM Scroggins, KJ Perschbach, AR Nair, TE Nishimura, SY Zhang, LN Agbor, J Wu, HL Keen, MC Naber, NA Pearson, KA Zimmerman, RM Weiss, NC Bowdler, YM Usachev, DA Santillan, MJ Potthoff, GL Pierce, KN Gibson-Cor, CD Sigmund, MK Santillan, JL Grobe
    JCI Insight, 2018;3(19):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  15. Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain
    Authors: JA Sullivan, LM Stanek, MJ Lukason, J Bu, SR Osmond, EA Barry, CR O'Riordan, LS Shihabuddi, SH Cheng, A Scaria
    Gene Ther., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  16. Household air pollution and angiogenic factors in pregnant Nigerian women: A randomized controlled ethanol cookstove intervention
    Authors: A Dutta, K Brito, G Khramstova, A Mueller, S Chinthala, D Alexander, D Adu, T Ibigbami, J Olamijulo, A Odetunde, K Adigun, L Pruitt, O Olopade, O Ojengbede, S Rana, CO Olopade
    Sci. Total Environ., 2017;599(0):2175-2181.
    Species: Human
    Sample Types: Plasma
  17. Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1
    Authors: M Eslani, I Putra, X Shen, J Hamouie, N Afsharkham, S Besharat, MI Rosenblatt, R Dana, P Hematti, AR Djalilian
    Invest. Ophthalmol. Vis. Sci., 2017;58(12):5507-5517.
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells
    Authors: AF Pantho, M Price, AZ Ashraf, U Wajid, ME Khansari, A Jahan, SH Afroze, MM Rhaman, CR Johnson, TJ Kuehl, MA Hossain, MN Uddin
    Int J Environ Res Public Health, 2017;14(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles
    Authors: M O'Brien, D Baczyk, JC Kingdom
    Sci Rep, 2017;7(1):5887.
    Species: Human
    Sample Types: Tissue Culture Supernates
  20. Low grade inflammation inhibits VEGF induced HUVECs migration in p53 dependent manner
    Authors: Sushil Panta
    Biochem. Biophys. Res. Commun, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. The anti-angiogenic role of soluble-form VEGF receptor in malignant gliomas
    Authors: Shingo Takano
    Int. J. Oncol, 2016;0(0):.
    Species: Human
    Sample Types: Tumor Extract Supernates
  22. Spectrum of Factors Triggering Endothelial Dysfunction in PIH
    Authors: VS Jammalamad, P Abraham
    J Clin Diagn Res, 2016;10(12):BC14-BC17.
    Species: Human
    Sample Types: Serum
  23. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
    Authors: Ingrid C Weel
    PLoS ONE, 2016;11(6):e0157584.
    Species: Human
    Sample Types: Tissue Homogenates
  24. Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia
    PLoS ONE, 2016;11(9):e0162652.
    Species: Human
    Sample Types: Plasma
  25. Inhibition of placental growth factor in renal cell carcinoma.
    Authors: Bessho H, Wong B, Huang D, Siew E, Huang D, Tan J, Ong C, Tan S, Matsumoto K, Iwamura M, Teh B
    Anticancer Res, 2015;35(1):531-41.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer.
    Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
    BMC Cancer, 2014;14(0):696.
    Species: Human
    Sample Types: Serum
  27. Placental growth factor and soluble Fms-like tyrosine kinase 1 in diabetic pregnancy: A possible relation to distal villous immaturity.
    Authors: El-Tarhouny S, Almasry S, Elfayomy A, Baghdadi H, Habib F
    Histol Histopathol, 2014;29(2):259-72.
    Species: Human
    Sample Types: Serum
  28. Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury.
    Authors: White W, Garrett A, Craici I, Wagner S, Fitz-Gibbon P, Butters K, Brost B, Rose C, Grande J, Garovic V
    PLoS ONE, 2014;9(3):e92693.
    Species: Human
    Sample Types: Serum
  29. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
    Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
    Br J Cancer, 2014;110(1):26-33.
    Species: Human
    Sample Types: Plasma
  30. FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.
    Authors: Owen, Leah A, Morrison, Margaux, Ahn, Jeeyun, Woo, Se Joon, Sato, Hajime, Robinson, Rosann, Morgan, Denise J, Zacharaki, Fani, Simeonova, Marina, Uehara, Hironori, Chakravarthy, Usha, Hogg, Ruth E, Ambati, Balamura, Kotoula, Maria, Baehr, Wolfgang, Haider, Neena B, Silvestri, Giuliana, Miller, Joan W, Tsironi, Evangeli, Farrer, Lindsay, Kim, Ivana K, Park, Kyu Hyun, DeAngelis, Margaret
    Invest Ophthalmol Vis Sci, 2014;55(6):3543-54.
    Species: Human
    Sample Types: Serum
  31. Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia.
    Authors: Huang Q, Wang S, Zhang M, Huang L, Tian J, Yu Y, Wang Z, Zhong M
    Placenta, 2013;34(10):949-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment.
    Authors: Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T
    PLoS ONE, 2013;8(4):e61483.
    Species: Human
    Sample Types: Serum
  33. Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies.
    Authors: Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S
    J Biol Chem, 2013;288(37):26800-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia.
    Authors: Liu, Linda Y, Yang, Ting, Ji, Jun, Wen, Qiaojun, Morgan, Alexande, Jin, Bo, Chen, Gongxing, Lyell, Deirdre, Stevenson, David K, Ling, Xuefeng, Butte, Atul J
    BMC Med, 2013;11(0):236.
    Species: Human
    Sample Types: Serum
  35. Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.
    Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
    Cytokine, 2013;61(3):755-8.
    Species: Human
    Sample Types: Serum
  36. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
    Authors: Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z
    Nature, 2012;485(7398):333-8.
    Species: Human
    Sample Types: Plasma
  37. In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer.
    Authors: Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, Thill M, Sehouli J, Kummel S
    Anticancer Res., 2011;31(8):2609-15.
    Species: Human
    Sample Types: Serum
  38. Prognostic significance of angiogenic factors in uterine cervical cancer.
    Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
    Anticancer Res., 2011;31(8):2589-95.
    Species: Human
    Sample Types: Serum
  39. Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
    Authors: Dubois SG, Shusterman S, Ingle AM, Ahern CH, Reid JM, Wu B, Baruchel S, Glade-Bender J, Ivy P, Grier HE, Adamson PC, Blaney SM
    Clin. Cancer Res., 2011;17(15):5113-22.
    Species: Human
    Sample Types: Plasma
  40. Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer.
    Authors: Rahbari NN, Schmidt T, Falk CS, Hinz U, Herber M, Bork U, Buchler MW, Weitz J, Koch M
    BMC Cancer, 2011;11(0):286.
    Species: Human
    Sample Types: Serum
  41. Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis.
    Authors: Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M
    Fertil. Steril., 2010;94(1):52-7.
    Species: Human
    Sample Types: Serum
  42. An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia.
    Authors: Verlohren S, Galindo A, Schlembach D, Zeisler H, Herraiz I, Moertl MG, Pape J, Dudenhausen JW, Denk B, Stepan H
    Am. J. Obstet. Gynecol., 2010;202(2):161.e1-161.e1.
    Species: Human
    Sample Types: Serum
  43. Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies.
    Authors: Powers RW, Jeyabalan A, Clifton RG
    PLoS ONE, 2010;5(10):e13263.
    Species: Human
    Sample Types: Serum
  44. Effect of smoking on circulating angiogenic factors in high risk pregnancies.
    Authors: Jeyabalan A, Powers RW, Clifton RG, Van Dorsten P, Hauth JC, Klebanoff MA, Lindheimer MD, Sibai B, Landon M, Miodovnik M, Caritis S, Roberts JM, Kuller J, Cotroneo M, Kamon T, Mercer B, Ramsey R, Paul R, Rabello Y, McCart D, Mueller E, Goldenberg R, Copper R, Sorokin Y, Norman G, Millinder A, Christmas JT, McCoy S, Elder S, Elder N, Carter B, Pemberton V, Thurnau G, Meier A, Minton V, Meis P, Swain M, Moawad AH, Jones P, Iams JD, Meadows S, Brenner S, Collins B, Newman RB, Carter SG, Romero R, Sabo V, Thom E, Bain RP, MacPherson C, Johnson D, Fischer ML, McNellis D, Spong C, Catz C, Yaffe S
    PLoS ONE, 2010;5(10):e13270.
    Species: Human
    Sample Types: Serum
  45. Periodic assessment of plasma sFlt-1 and PlGF concentrations and its association with placental morphometry in gestational hypertension (GH) - a prospective follow-up study.
    Authors: Jeevaratnam K, Nadarajah VD, Judson JP
    BMC Pregnancy Childbirth, 2010;10(0):58.
    Species: Human
    Sample Types: Plasma
  46. Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice.
    Authors: Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T
    Am. J. Physiol. Renal Physiol., 2010;298(3):F609-16.
    Species: Human
    Sample Types: Urine
  47. Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.
    Authors: Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, Heikura T, Toivanen P, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S
    Mol. Ther., 2009;17(2):278-84.
    Species: Human
    Sample Types: Plasma
  48. Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study.
    Authors: Levine RJ, Vatten LJ, Horowitz GL
    BMJ, 2009;339(0):b4336.
    Species: Human
    Sample Types: Serum
  49. Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study.
    Authors: Sandhofer A, Tatarczyk T, Kirchmair R, Iglseder B, Paulweber B, Patsch JR, Schratzberger P
    Atherosclerosis, 2009;206(1):265-9.
    Species: Human
    Sample Types: Plasma
  50. Natural selection of FLT1 alleles and their association with malaria resistance in utero.
    Authors: Muehlenbachs A, Fried M, Lachowitzer J, Mutabingwa TK, Duffy PE
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(38):14488-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  51. Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
    Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
    J. Am. Coll. Cardiol., 2008;52(5):387-93.
    Species: Human
    Sample Types: Plasma
  52. Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia.
    Authors: Jeyabalan A, Powers RW, Durica AR, Harger GF, Roberts JM, Ness RB
    Am. J. Hypertens., 2008;21(8):943-7.
    Species: Human
    Sample Types: Plasma
  53. Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis.
    Authors: Gutman G, Barak V, Maslovitz S, Amit A, Lessing JB, Geva E
    Fertil. Steril., 2008;89(4):922-6.
    Species: Human
    Sample Types: Serum
  54. Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction.
    Authors: Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D
    Clin. Sci., 2007;112(1):51-7.
    Species: Human
    Sample Types: Serum
  55. Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction.
    Authors: Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard JF, Pouplin S, Boumier P, Vittecoq O, Le Loet X, Boissier MC
    Clin. Immunol., 2007;124(2):158-64.
    Species: Human
    Sample Types: Serum
  56. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
    Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
    Cancer Lett., 2007;248(1):131-6.
    Species: Human
    Sample Types: Plasma
  57. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients.
    Authors: Caine GJ, Ryan P, Lip GY, Blann AD
    Cancer Lett., 2007;251(2):296-301.
    Species: Human
    Sample Types: Plasma
  58. Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis.
    Authors: Masuyama H, Suwaki N, Nakatsukasa H, Masumoto A, Tateishi Y, Hiramatrsu Y
    Am. J. Obstet. Gynecol., 2006;194(2):551-6.
    Species: Human
    Sample Types: Serum
  59. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.
    Authors: Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA
    N. Engl. J. Med., 2006;355(10):992-1005.
    Species: Human
    Sample Types: Serum
  60. Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia.
    Authors: Buhimschi CS, Norwitz ER, Funai E, Richman S, Guller S, Lockwood CJ, Buhimschi IA
    Am. J. Obstet. Gynecol., 2005;192(3):734-41.
    Species: Human
    Sample Types: Urine
  61. Urinary placental growth factor and risk of preeclampsia.
    Authors: Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
    JAMA, 2005;293(1):77-85.
    Species: Human
    Sample Types: Urine
  62. Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta.
    Authors: Li H, Gu B, Zhang Y, Lewis DF, Wang Y
    Placenta, 2005;26(2):210-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours.
    Authors: Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, Morgan B, Lebwohl D, Masson E, Ho YY, Gunther C, Laurent D, Unger C
    Eur. J. Cancer, 2005;41(9):1291-9.
    Species: Human
    Sample Types: Serum
  64. Circulating angiogenic factors and the risk of preeclampsia.
    Authors: Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
    N. Engl. J. Med., 2004;350(7):672-83.
    Species: Human
    Sample Types: Serum
  65. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
    Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
    Immunity, 2004;21(6):831-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  66. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
    Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
    J. Clin. Invest., 2003;111(5):649-58.
    Species: Human
    Sample Types: Serum

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Human VEGFR1/Flt-1 Quantikine ELISA Kit
By Anonymous on 08/26/2020
Application: Sample Tested: HUVEC human umbilical vein endothelial cells