Interleukin 18 binding proteins are secreted glycoproteins which antagonize IL-18 activity by binding IL-18 and blocking its biological activity. Alternative splicing of the IL-18 BP gene produces at least four isoforms that differ in affinity for IL-18. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain while isoforms b and d lack a complete Ig-like domain.
IL-18 BPd Antibody [DyLight 350]
Novus Biologicals | Catalog # AF122D
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot, ELISA, Neutralization
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL‑18 BPd
Thr27-Ala191
Accession # AAD17194
Thr27-Ala191
Accession # AAD17194
Specificity
Detects mouse IL‑18 BPd in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for IL-18 BPd Antibody [DyLight 350]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-18 BPd
Long Name
Interleukin 18 Binding Protein Isoform d
Alternate Names
IL18 BPd
Gene Symbol
IL18BP
Additional IL-18 BPd Products
Product Documents for IL-18 BPd Antibody [DyLight 350]
Product Specific Notices for IL-18 BPd Antibody [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
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- Western Blot Troubleshooting
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- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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