IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

Novus Biologicals | Catalog # NBP3-57730

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Sample Type

Cell culture supernatants from mice (Mus musculus). Additional biological sample types reported in the literature: serum, plasma, bronchoalveolar lavage fluid (BALF), intestinal tissue lysates, liver homogenates, and splenocyte culture supernatants. (100 ul)

Reactivity

Mouse
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Product Specifications

Description

Contains a capture antibody, detection antibody, and recombinant protein standard for assay development. These antibodies have been validated to function together in an ELISA format using the provided standard. Optimal buffers, antibody concentrations, incubation times, temperatures, and assay conditions have not been predetermined, allowing researchers to optimize assay sensitivity and dynamic range based on their specific sample type and experimental requirements. The quantities of components are not matched, and individual components may be purchased separately. This product is for research use only.

Sample Volume Required

100 ul

Conjugate

Biotin

Scientific Data Images for IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

ELISA: IL-28B/IFN-lambda 3 Antibody Pair [Biotin] [NBP3-57730] -

Representative standard curve for IL-28B/IFN-lambda 3 Antibody Pair [Biotin] (NBP3-57730)

Kit Contents for IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

  • Capture Antibody (1 Set = <= 10 Plates; 2 Set = <= 20 Plates): (Catalog # <a href= /products/il-28b-ifn-lambda-3-antibody_nbp3-57637 >NBP3-57637</a>)
  • Detection Antibody (Biotinylated): (Catalog # <a href= "/products/il-28b-ifn-lambda-3-antibody_nbp3-57669" >NBP3-57669</a>)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL-28B/IFN-lambda 3

Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 28B

Alternate Names

IFN-lambda 3

Gene Symbol

IFNL3

Additional IL-28B/IFN-lambda 3 Products

Product Documents for IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-28B/IFN-lambda 3 Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Related Research Areas

Interferons

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Associated Pathways

Toll-Like Receptor Signaling Pathways
Toll-Like Receptor Signaling Pathway Thumbnail