IP6K3 Antibody

Novus Biologicals | Catalog # NBP1-45229

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine, Canine

Applications

Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Peptide with sequence RLCSEYPENKRHR corresponding to internal region according to NP_473452.2.

Epitope

internal region

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Applications for IP6K3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000
Application Notes
WB: Preliminary experiments gave an approx. 37 kDa band in human brain (cerebral cortex and hippocampus) and mouse brain lysates after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 46.4 kDa band according to NP_473452.2. The 37 kDa band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IP6K3

IP6K3, also known as Inositol hexakisphosphate kinase 3, is a 46 kDa 410 amino acid protein, and is involved in the transformation of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate. This protein has also been shown to have interactions with HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, and HIST1H2BI in the inositol pyrophosphates biosynthesis and metabolism pathway. Disease research is currently being studied with relation to IP6K3 and lupus erythematosus and malaria.

Alternate Names

IHPK3ATP:1D-myo-inositol-hexakisphosphate phosphotransferase, inositol hexakisphosphate kinase 3, Inositol hexaphosphate kinase 3EC 2.7.4.21, InsP6 kinase 3, INSP6K3MGC102928

Entrez Gene IDs

117283 (Human); 271424 (Mouse); 688862 (Rat)

Gene Symbol

IP6K3

Additional IP6K3 Products

Product Documents for IP6K3 Antibody

Certificate of Analysis

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Product Specific Notices for IP6K3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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