Kir2.2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-46385

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Serum

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

potassium inwardly-rectifying channel, subfamily J, member 12. (Uniprot# Q14500)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Kir2.2 Antibody - BSA Free

Kir2.2 Antibody - BSA Free

Western Blot: Kir2.2 Antibody - BSA Free [NBP3-46385] -

Western Blot: Kir2.2 Antibody - BSA Free [NBP3-46385] - Mouse lung tissue were subjected to SDS PAGE followed by western blot with (Kir2.2 antibody) at dilution of 1:1500

Applications for Kir2.2 Antibody - BSA Free

Application
Recommended Usage

Serum

FC

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 45-50 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Kir2.2

FUNCTION: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Tissue specificity: Highest level in cerebellum. Moderately found in kidney, forebrain and skeletal muscle. Not detected in uterus, liver and pancreas. Subcellular location: Membrane, Multi-pass membrane protein.

Long Name

ATP-sensitive inward rectifier potassium channel 12

Alternate Names

IRK-2, IRK2, KCNJ12, KCNJN1

Gene Symbol

KCNJ12

Additional Kir2.2 Products

Product Documents for Kir2.2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Kir2.2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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