L-Dehydroascorbic acid
Tocris Bioscience | Catalog # 5734
Key Product Details
Description
Product Description
L-Dehydroascorbic acid is a oxidized form of L-Ascorbic acid (Cat. No. 4055). Transported into cells through GLUT1. Selectively induces cell death in KRAS and BRAF mutant cells in vitro.
Product Specifications for L-Dehydroascorbic acid
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 1.74 | 10 with gentle warming | |
| DMSO | 17.41 | 100 |
Preparing Stock Solutions for L-Dehydroascorbic acid
The following data is based on the product molecular weight 174.11.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.74 mL | 28.72 mL | 57.43 mL |
| 5 mM | 1.15 mL | 5.74 mL | 11.49 mL |
| 10 mM | 0.57 mL | 2.87 mL | 5.74 mL |
| 50 mM | 0.11 mL | 0.57 mL | 1.15 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Yun Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science 2015 PMID: 26541605
- Kaiser Vitamin C could target some common cancers. Science 2015 PMID: 26542550
Product Documents for L-Dehydroascorbic acid
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for L-Dehydroascorbic acid
For research use only
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