L-DOPA Antibody

Novus Biologicals | Catalog # NBP3-06881

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Non-species specific

Cited:

Mouse

Applications

Validated:

ELISA, Dot Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all L-DOPA Primary Antibodies »

Product Specifications

Immunogen

The immunogen used to generate this antibody corresponds to Levodopa (L-DOPA)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for L-DOPA Antibody

Application
Recommended Usage

ELISA

1:1000-1:10000
Application Notes
Dot blot-Assay dependent.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.025% Proclin 300

Concentration

0.35 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: L-DOPA

L Dopa is an intermediate in dopamine biosynthesis. Clinically, L Dopa is used in the management of Parkinson's disease. It is used as a prodrug to increase dopamine levels since it is able to cross the blood-brain barrier whereas dopamine itself cannot. Once L Dopa has entered the central nervous system (CNS), it is metabolised to dopamine by aromatic L amino acid decarboxylase. This also occurs in the peripheral tissues, causing adverse effects and decreasing the available dopamine to the CNS, so it is standard practice to co administer a peripheral DOPA decarboxylase inhibitor and often a catechol-O-methyl transferase (COMT) inhibitor. The antiserum was tested using the free floating PAP technique on rat dopaminergic areas. The anti-conjugated L-DOPA antibodies gave a good staining between 1/2000-1/5000 dilution in these areas.

Alternate Names

3 4 dihydroxy L phenylalanine, L dihydroxyphenylalanine, Levodopa

Additional L-DOPA Products

Product Documents for L-DOPA Antibody

Certificate of Analysis

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Product Specific Notices for L-DOPA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for L-DOPA Antibody

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