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LaKe

Catalog #: 8888 Datasheet / COA / SDS
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8888/100

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LaKe | Buffers, Chelators and Reagents
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Description: Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

Chemical Name: (3R)-3-Hydroxybutyl (2S)-2-hydroxypropanoate and (1R)-3-Hydroxy-1-methylpropyl (2S)-2-hydroxypropanoate

Purity: ≥95%

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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

LaKe is a metabolite that undergoes hydrolytic conversion to yield (S)-lactate (Lac) and (R)-1,3-butanediol (BHB) in cells, two metabolites naturally released during strenuous exercise and prolonged fasting. In vivo, oral ingestion of LaKe in rats, results in an increase of Lac and BHB plasma levels, triggering reduced lipolysis and elevation of the appetite-suppressing compound Lac-Phe (Cat. No. 7942).

Technical Data

M.Wt:
162.19
Formula:
C7H14O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Mmimetika Biosciences

Product Datasheets

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