LaKe
Tocris Bioscience | Catalog # 8888
Key Product Details
Description
Product Description
LaKe is a metabolite that undergoes hydrolytic conversion to yield (S)-lactate (Lac) and (R)-1,3-butanediol (BHB) in cells, two metabolites naturally released during strenuous exercise and prolonged fasting. In vivo, oral ingestion of LaKe in rats, results in an increase of Lac and BHB plasma levels, triggering reduced lipolysis and elevation of the appetite-suppressing compound Lac-Phe (Cat. No. 7942).
Licensing Information
Sold under license from Mmimetika Biosciences
Product Specifications for LaKe
Molecular Weight
Formula
Storage
Purity
Chemical Name
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 16.22 | 100 |
Preparing Stock Solutions for LaKe
The following data is based on the product molecular weight 162.19.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.17 mL | 30.83 mL | 61.66 mL |
| 5 mM | 1.23 mL | 6.17 mL | 12.33 mL |
| 10 mM | 0.62 mL | 3.08 mL | 6.17 mL |
| 50 mM | 0.12 mL | 0.62 mL | 1.23 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Ottosen Preparation and preclinical characterization of a simple ester for dual exogenous supply of lactate and beta-hydroxybutyrate. J.Agric.Food Chem. 2024 PMID: 39214666
Product Documents for LaKe
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for LaKe
For research use only
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