LEP (116-130) (mouse)

Name: LEP (116-130) (mouse)
Brand: Tocris Bioscience
SKU: 2985

Tocris Bioscience | Catalog # 2985

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Product Documents

Synthetic leptin peptide fragment

Discontinued Product

2985 has been discontinued. View all Leptin Receptor Peptides products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Synthetic leptin peptide fragment

View all Leptin Receptor Peptides »

Product Description

LEP (116-130) (mouse) is a synthetic leptin peptide fragment. Restricts weight gain and reduces food intake in female mice lacking endogenously circulating active leptin.

Product Specifications for LEP (116-130) (mouse)

Molecular Weight

1560.73

Formula

C₆₄H₁₀₉N₁₉O₂₄S

Storage

Desiccate at -20°C

CAS Number

258276-95-8

PubChem ID

90471193

InChI Key

YEHDWBRMEXDYLT-RDEOYNLOSA-N

SMILES

[H]N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Grasso Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes 1999 PMID: 10535455
Rozhavskaya Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis and thermoregulation. Endocrinology 2000 PMID: 10875251
Grasso In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140. Endocrinology 1997 PMID: 9075696

Product Documents for LEP (116-130) (mouse)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for LEP (116-130) (mouse)

For research use only

Related Research Areas

Glucose Homeostasis

Metabolic Peptide Hormones and Regulators

Nutrition and Appetite

Obesity

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