Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.
Mouse TACE/ADAM17 (AAC62934.1) VersaClone cDNA
R&D Systems | Catalog # RDC3427
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TACE/ADAM17
Long Name
TNF-alpha Converting Enzyme
Alternate Names
ADAM17, CD156b
Gene Symbol
ADAM17
UniProt
Additional TACE/ADAM17 Products
Product Documents for Mouse TACE/ADAM17 (AAC62934.1) VersaClone cDNA
Product Specific Notices for Mouse TACE/ADAM17 (AAC62934.1) VersaClone cDNA
For research use only
Related Research Areas
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Associated Pathways
Notch Signaling Pathways
