PNMA2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47103

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

paraneoplastic antigen MA2. (Uniprot# Q9UL42)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PNMA2 Antibody - BSA Free

PNMA2 Antibody - BSA Free

Western Blot: PNMA2 Antibody - BSA Free [NBP3-47103] -

Western Blot: PNMA2 Antibody - BSA Free [NBP3-47103] - Jurkat cells were subjected to SDS PAGE followed by western blot with (PNMA2 antibody) at dilution of 1:2000

Applications for PNMA2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PNMA2

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.

Alternate Names

MA2KIAA0883, MM2, Onconeuronal antigen Ma2, paraneoplastic antigen MA2,40 kDa neuronal protein, Paraneoplastic neuronal antigen MM2, retrotransposon gag domain containing 2, RGAG2

Gene Symbol

PNMA2

Additional PNMA2 Products

Product Documents for PNMA2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PNMA2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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