pre-mRNA cleavage factor I (59 kDa subunit) Antibody

Novus Biologicals | Catalog # NB100-61599

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all pre-mRNA cleavage factor I (59 kDa subunit) Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human cleavage and polyadenylation specificity factor 7, 59 kDa subunit using the numbering given in entry NP_079087.2 (GeneID 79869).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for pre-mRNA cleavage factor I (59 kDa subunit) Antibody

Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NB100-61599]

Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NB100-61599]

Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NB100-61599] - Detection of Human CPSF59 on HeLa whole cell lysate using NB100-61599. CPSF59 was also immunoprecipitated by rabbit anti-CPSF59 antibody NB100-61600.

Applications for pre-mRNA cleavage factor I (59 kDa subunit) Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: pre-mRNA cleavage factor I (59 kDa subunit)

CPSF59 is the the 59 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3'-end processing. CPSF59 bears an RNA-recognition motif (RRM).

Alternate Names

CFIm59, cleavage and polyadenylation specific factor 7, 59kDa, CPSF 59 kDa subunit, FLJ12529,59 kDa subunit, FLJ39024, MGC9315, pre-mRNA cleavage factor I, 59 kDa subunit

Entrez Gene IDs

79869 (Human)

Gene Symbol

CPSF7

UniProt

NP_079087.2 (Human)

Additional pre-mRNA cleavage factor I (59 kDa subunit) Products

Product Documents for pre-mRNA cleavage factor I (59 kDa subunit) Antibody

Certificate of Analysis

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Product Specific Notices for pre-mRNA cleavage factor I (59 kDa subunit) Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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