PRMT7 Antibody - BSA Free

Novus Biologicals | Catalog # NB100-56400

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PRMT7 Primary Antibodies »

Product Specifications

Immunogen

Amino acids 346-360 of human PRMT7 were used as the immunogen.

Specificity

The amino acid sequence used as immunogen can be found in five different human PRMT7 isoforms: CRA_a (692 amino acids), CRA_b (613 amino acids), CRA_c (465 amino acids), CRA_d (655 amino acids) and CRA_e (567 amino acids).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRMT7 Antibody - BSA Free

Western Blot: PRMT7 Antibody [NB100-56400]

Western Blot: PRMT7 Antibody [NB100-56400]

Western Blot: PRMT7 Antibody [NB100-56400] - Analysis of PRMT7 in A) HeLa and B) NIH 3T3 cell lysate using this antibody at 2 ug/ml.

Applications for PRMT7 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRMT7

Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. The PRMT proteins are recruited by C-terminal activation domain-2 of the SRC (steroid receptor coactivator) GRIP-1, whereas p300 interacts with activation domain-1 in the C terminus. have identified a mammalian arginine N-methyltransferase, PRMT7, that can catalyze the formation of omega-NG-monomethyl arginine in peptides. In contrast to the other members of the PRMT family, PRMT7 was not able to methylate GST-fibrillarin or myelin basic protein or histone H2A, in vitro. It is also structurally different from other PRMTS in containing two putative AdoMet-binding motifs. Both of these domains are required for enzymatic activity.

Long Name

Protein arginine N-methyltransferase 7

Alternate Names

EC 2.1.1.321, KIAA1933

Entrez Gene IDs

54496 (Human); 214572 (Mouse)

Gene Symbol

PRMT7

UniProt

Q9NVM4 (Human)

Additional PRMT7 Products

Product Documents for PRMT7 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PRMT7 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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