Pseudo RACK1

Name: Pseudo RACK1
Brand: Tocris Bioscience
SKU: 1790

Tocris Bioscience | Catalog # 1790

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Product Documents

Protein kinase C activator peptide (attached to cell permeable vector)

Discontinued Product

1790 has been discontinued. View all Protein Kinase C Activators products.

Technical Data
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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Protein kinase C activator peptide (attached to cell permeable vector)

View all Protein Kinase C Activators »

Product Description

Pseudo RACK1 is an activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the activator peptide. Once inside the cell, the disulfide bonds are subjected to reduction in the cytoplasm leading to release of the activator peptide.

Product Specifications for Pseudo RACK1

Molecular Weight

3198.81

Formula

C₁₄₄H₂₂₅N₄₃O₃₄S₃

Storage

Store at -20°C

PubChem ID

90488710

InChI Key

LTAVZZKCZYNJEE-PMCSTDROSA-N

SMILES

[H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

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音量

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Background References

References are publications that support the biological activity of the product.

Ron and Mochly-Rosen An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc.Natl.Acad.Sci.U.S.A. 1995 PMID: 7831317
Theodore Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J.Neurosci. 1995 PMID: 7472470
Derossi The third helix of the antennapedia homeodomain translocates through biological membranes. J.Biol.Chem. 1994 PMID: 8144628

Product Documents for Pseudo RACK1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Pseudo RACK1

For research use only

Related Research Areas

Diabetes

Intracellular Kinases

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