PTRF Antibody

Novus Biologicals | Catalog # NB100-60635

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Western Blot, Immunoprecipitation

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all PTRF Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 238 and 288 human RNA polymerase I and transcript release factor using the numbering given in entry NP_036364.2 (GeneID 284119).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTRF Antibody

Western Blot: PTRF Antibody [NB100-60635]

Western Blot: PTRF Antibody [NB100-60635]

Western Blot: PTRF Antibody [NB100-60635] - Detection of Human and Mouse PTRF on HeLa whole cell lysate using NB100-60635. PTRF was also immunoprecipitated by rabbit anti-PTRF antibodies NB100-60633 and NB100-60634.

Applications for PTRF Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PTRF

PTRF (polymerase I and transcript release factor) was first identified as a TTF-I and RNA polymerase I (RNA Pol I) interacting protein that functions in the termination of RNA polymerase I transcription. PTRF has also been described as a protein that localizes to the plasma membrane and caveolae of adipocytes and whose localization is under the control of insulin. In this context, PTRF has been observed to associate with a lipase and have an extranuclear role in the regulation of lipolysis. PTRF is also known as FKSG13.

Alternate Names

CAVIN, Cavin-1, CGL4, FLJ90031, polymerase I and transcript release factor, RNA polymerase I and transcript release factor, TTF-I interacting peptide 12

Entrez Gene IDs

284119 (Human); 19285 (Mouse)

Gene Symbol

CAVIN1

UniProt

Q6NZI2 (Human)

Additional PTRF Products

Product Documents for PTRF Antibody

Certificate of Analysis

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Product Specific Notices for PTRF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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